SPRAVATO®
What Is Spravato (esketamine)?
Spravato is considered by many to be one of the biggest breakthroughs in depression treatment since the advent of Prozac. Spravato is the brand name for esketamine which is used in treating treatment-resistant depression and acute suicidal thinking.
Spravato is FDA-approved, prescribed by a psychiatrist or psychiatric nurse practitioner, and administered in a controlled environment. It is self-administered intranasally in the office under the care and supervision of an on-site registered nurse or trained technician. The effects of Spravato are felt within hours, compared to traditional depression medication which can take several weeks to months to take effect. Spravato can serve as a catalyst for therapeutic growth for many for whom more traditional mental health interventions have fallen short.
FDA Approval and Patient Eligibility
Spravato was first approved by the FDA for use alongside other antidepressants for treating treatment-resistant depression in adults in 2019. In August of 2020, the FDA expanded their approval to allow Spravato treatment in patients struggling with suicidality. At Curated, we offer Spravato treatment to patients who qualify under their insurance plan’s criteria as well as to those who wish to pay privately and are deemed clinically appropriate. Though it varies between policies, most insurance companies require at least two prior trials of antidepressants and for an individual to be taking an oral antidepressant during the course of treatment with Spravato. While we can negotiate with most insurance plans to get the medication itself covered, office visits are often only covered for Cigna, United and Medicare patients, for whom we have clinicians who are in-network.
Spravato Efficacy Statistics
Clinical trials of Spravato treated patients showed a 69% response rate.
Clinical trials of Spravato treated patients showed a 52% remission rate.
Most patients undergoing Spravato treatment will begin to feel effects within four weeks, if not sooner. Learn more about Spravato efficacy.
What to Expect When Getting Spravato
Spravato treatment and experience varies from patient to patient. Most often, the experience is guided by patients’ own intentions and treatment goals. The facilitator will be on-site and nearby for the duration of your treatment to answer any questions you may have, or assist with other requests as needed.